الأدوية التي تستخدم في علاج التهاب المفاصل

[shimaa sherif]

?What drugs are used to treat rheumatoid arthritis

The drugs used to treat rheumatoid arthritis can be divided into two groups:

• Drugs that decrease pain and local inflammation include aspirin and non-steroidal anti-inflammatory drugs or NSAIDS (such as ibuprofen or naproxen).
• Drugs that decrease pain and inflammation while decreasing the growth of abnormal synovial tissue (the tissue that lines the inside of the joint). These drugs include methotrexate and low doses of corticosteroids (such as prednisone or cortisone). In some people, these drugs also decrease joint destruction.

Other medications used to treat rheumatoid arthritis include: anti-malarial medications (such as hydroxychloroquine), gold, sulfasalazine, penicillamine, cyclophosphamide, cyclosporin and minocycline. Sometimes, more than one drug may be prescribed.
Newer biologic agents which block the effects of specific inflammatory factors (cytokines) are now available. Infliximab, etanercept and adalimumab block the cytokine anti-tumor necrosis alpha, and anakinra blocks the cytokine interleukin-1. These agents are somewhat more effective than previous medicines and can be combined with them, especially with methotrexate.

?How well do the drugs work

All the drugs used to treat rheumatoid arthritis have been tested in patients who have the disease and have been proven useful.
All of the NSAIDs are similarly effective, making it difficult for doctors to strongly recommend one over the other.
Methotrexate is among the drugs which are most effective in providing long-term benefits for people with rheumatoid arthritis.

?Are the drugs dangerous

The effectiveness and the risks of drugs are considered when your rheumatologist plans your treatment.
If a drug is very effective in treating an illness but causes a lot of side effects, it is not an ideal treatment. For example, high doses (15 to 20 mg or more per day) of corticosteroids can make people with rheumatoid arthritis feel dramatically better. However, high doses of corticosteroids may cause serious side effects when taken over many months or years.
In addition, NSAIDs are no more effective than full doses of uncoated aspirin, yet they are often prescribed because they are not as irritating to the stomach. Coated aspirin, such as Ecotrin, is much less irritating to the stomach than the same uncoated medicine.

?What are some of the side effects of the drugs

Since no drug is entirely safe, your doctor will talk to you about the possible benefits from the drugs as well as the risks and side effects. The occurrence of side effects depends on the dose, type of medication and length of treatment.
Some of the side effects of each type of drug used to treat rheumatoid arthritis are listed below.
Please note: the following side effects are the most common. All possible side effects are not included. Always contact your doctor if you have questions about your personal situation.
NSAIDs may cause the following side effects:

• Heartburn
• Stomach pain
• Ulcers
• Nausea and vomiting
• Diarrhea and/or constipation
• Fluid retention
• Worsened high blood pressure and/or kidney problems

Methotrexate can cause the following side effects:

• Upset stomach
• Mild hair loss
• Mouth sores
• Temporary decrease in red blood cells, white blood cells and platelets
• Liver damage
• Inflammation of the lungs (rare)

NOTE: Methotrexate may not be recommended for people who have kidney, lung or liver problems.
Corticosteroids (often called steroids) can cause the following side effects:

• Easy bruising
• Osteoporosis (bone weakening disease)
• Cataracts
• Weight gain
• Increased risk of infections
• Diabetes
• High blood pressure

NOTE: Many of the side effects (as well as the benefits) of steroids are directly related to the dose that is prescribed. Certain people with rheumatoid arthritis can take daily low doses of cortisone with minimal risk and great benefits.
The newer biologic agents can cause the following side effects:

• Increased likelihood and worsening of certain infections, especially tuberculosis
• Neurologic symptoms like multiple sclerosis
• Higher likelihood of lymphoma (cancer of the lymph system)

Source ;
Cleveland clinic

[ديمه]

شكرا ليكي دكتوره رهوفه موضوع جميل كمان بستخدمو paracetamol للروماتيزم

[Dr-Mohammed_714s]

Thank you Dr.rahaf for your Effort

[alrahman]

موضوع جميل رهوف بس لى بعض الاسئلة
diprofos amp تكتب كتير فى روشتات العظام ولانها فعالة يكررها الكثير وده خطا نتيجة اضرارهاايه المدة المسموحة لتكرار هذه الامبول وايضاM P A
ثانيا امراة 45 عام تعانى من الم شديد بمفصل الركبة من الخلف فهى لا تستطيع ثنى هذا المفصل وبها دوالى بساقها ممكن انصحها بايه ؟

[sucess is amust]

شكراا ع الموضوع

methotrexate belonged to class called DMARD disease modified antirhematoid drugs
cause decrease to folic acid
فدايما بيوصف معاه
folic acid
فى حالات الروماتويد
لتعويض هذا النقص

[farha]

الله يعطيك العافية د.رهف والموضوع شيق جدا يسلمو ايديك

[زهور أحمد]

شكرا جزيلا موضوع رائع ومفيد

[احمد ابراهيم الديهى]

اريد مضاد لالتهاب عظمة الحوض والعضلة الضامة